Liquid antisolvent precipitation process for solubility modulation of bicalutamide
نویسندگان
چکیده
منابع مشابه
Liquid antisolvent precipitation process for solubility modulation of bicalutamide.
Liquid antisolvent process was explored as a solubility modulating tool. Bicalutamide, a poorly water soluble drug, was used as a candidate. Low aqueous solubility and poor dissolution of bicalutamide results into poor and variable bioavailability. Therefore, the objective of the present work was to modify the solubility of bicalutamide using the liquid antisolvent precipitation process. HPMC E...
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ژورنال
عنوان ژورنال: Acta Pharmaceutica
سال: 2011
ISSN: 1846-9558,1330-0075
DOI: 10.2478/v10007-011-0036-0